Explore the Alzheimer’s Disease Proteome
The database contains the results of a series of proteomics experiments performed using Liquid-chromatography-Mass spectrometry (LC-MS) on human brain samples to compare protein expression levels between individuals with Alzheimer’s Disease and age-matched controls.
Data have been analysed using a validated Bayesian statistical pipeline which produces a probability distribution for the relative expression of each protein between classes. These distributions, along with the data for each individual sample in the experiment, are also provided from the search results.
Full details of this study, including patient metadata, methodology and key findings, as well a description of this resource, can be found in the associated paper (Xu et al, “Localised protein expression changes in human Alzheimer’s brain correlate with disease progression” Submitted.).